Product Description
Known For: Charleston’s only ketamine clinic that also specializes in opioid addiction treatment — offering IV ketamine infusions alongside Medication-Assisted Treatment (MAT) and Suboxone for a patient population where depression and substance use often coexist.
| Review Scores | Positive reviews; patients praise the dual focus on mood disorders and addiction treatment |
| Location | Mount Pleasant, SC |
| Address | 1435 Stuart Engals Blvd, Suite 101, Mount Pleasant, SC 29464 |
| Phone | (843) 800-5686 |
| Website | tidewaterhealth.org |
| Treatments | IV Ketamine Infusion, Medication-Assisted Treatment (MAT) for Opioid Use Disorder, Suboxone |
| Conditions Treated | Treatment-Resistant Depression, Anxiety, PTSD, Chronic Pain, Opioid Use Disorder |
| Cost | Contact for pricing |
| Insurance | Contact for insurance details |
| Clinical Lead | Medical team specializing in ketamine infusion and addiction medicine |
HealingMaps Take: Tidewater Health & Ketamine Center occupies a unique niche in the Charleston market by combining ketamine infusion therapy with addiction medicine. This dual focus is clinically significant: treatment-resistant depression and opioid use disorder frequently co-occur, and patients struggling with both conditions have historically fallen through the cracks — ketamine clinics would not treat active substance use, and addiction clinics did not offer ketamine. Tidewater bridges that gap. The Stuart Engals Boulevard location in Mount Pleasant provides a medical office setting that is accessible from both sides of the Cooper River. The Suboxone/MAT program means patients can receive their opioid addiction treatment and their depression treatment at the same practice, reducing the logistical burden that causes so many dual-diagnosis patients to drop out of care. For patients in the Charleston metro who are dealing with treatment-resistant depression alongside opioid use disorder — or for those whose chronic pain led them down both the depression and the opioid path — Tidewater offers an integrated model that understands the intersection.
Patient Review
“Tidewater understood that my depression and my opioid use were connected in a way no other provider ever acknowledged. Getting ketamine infusions and my Suboxone at the same clinic meant I actually stuck with both treatments. The staff treats you with dignity regardless of your history.”
About Tidewater Health & Ketamine Center
Tidewater Health & Ketamine Center is located at 1435 Stuart Engals Blvd, Suite 101, Mount Pleasant, SC 29464. The clinic provides IV ketamine infusion therapy for treatment-resistant depression, anxiety, PTSD, and chronic pain, alongside Medication-Assisted Treatment (MAT) including Suboxone for opioid use disorder. Tidewater serves Mount Pleasant, Charleston, North Charleston, Summerville, and the greater Lowcountry.
For more on how ketamine therapy works, see our complete guide to ketamine therapy.
What People Like
Only Charleston ketamine clinic also offering addiction medicine (MAT/Suboxone). Addresses co-occurring depression and substance use under one roof. Mount Pleasant location accessible from both sides of the Cooper River. Reduces logistical burden for dual-diagnosis patients. Dignified treatment environment regardless of patient history.
What People Don’t Like
No KAP or psychotherapy integration. Pricing not published. Insurance details not clearly listed on website. Addiction medicine focus may not appeal to patients without substance use history. Limited online review volume. No Spravato option listed.
Getting Started at Tidewater Health & Ketamine Center
Call (843) 800-5686 or visit tidewaterhealth.org to schedule a consultation. Located at 1435 Stuart Engals Blvd, Suite 101, Mount Pleasant, SC 29464. Open Monday-Friday 8am-4pm.
Learn more about the evidence behind ketamine for depression at the National Institute of Mental Health.
Reviews
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