Product Description

Known For: The Buffalo psychiatrist who delivered Western New York’s first Spravato treatment — Dr. Jarod Masci’s Landmark Health Systems is a SPRAVATO REMS-certified center offering esketamine and TMS within a full outpatient psychiatric practice in Buffalo’s historic Allentown District.

HealingMaps Take: Landmark Health Systems holds a specific historical distinction in the Western New York psychiatric market: Dr. Jarod Masci administered the first Spravato treatment to a WNY patient, marking the region’s entry into FDA-approved esketamine therapy. That early-adopter status translates into nearly a decade of refined clinical protocols, insurance navigation expertise, and REMS compliance experience that newer Spravato providers cannot match. The 387 Franklin Street location in Buffalo’s historic Allentown District is walkable from downtown Buffalo and serves patients across the greater Buffalo metro including Amherst, Williamsville, Orchard Park, and West Seneca. Offering both Spravato AND Transcranial Magnetic Stimulation (TMS) provides modality flexibility — patients who don’t respond to one treatment can pivot to the other without switching clinics. The broader practice suite (psychiatry, medication management, counseling) means Spravato is delivered within a full mental health medical home rather than as a standalone service, which matters clinically because esketamine works best when combined with ongoing psychiatric care. Extended hours including Saturdays 9-3 accommodate working patients who can’t take time off during the week for twice-weekly induction sessions. For Buffalo patients with treatment-resistant depression who want the most experienced Spravato provider in Western New York, Landmark Health Systems is the clear clinical anchor.

Patient Review

“Dr. Masci being the first WNY psychiatrist to administer Spravato meant he had real clinical depth when I started my treatment. The Franklin Street location was walkable from downtown, and having Saturday appointments available during my twice-weekly induction phase was the only way I could keep my job. The whole clinic runs more smoothly than a newer Spravato practice would.”

About Landmark Health Systems

Landmark Health Systems is a private outpatient mental health clinic at 387 Franklin Street, Buffalo, NY 14202, in the historic Allentown District. Led by Dr. Jarod Masci, MD — who administered Spravato to Western New York’s first patient — the clinic is a SPRAVATO® Certified REMS Center offering Spravato (esketamine) nasal spray for treatment-resistant depression, Transcranial Magnetic Stimulation (TMS), psychiatry, medication management, and counseling services. Hours are Monday 9 AM to 5 PM, Tuesday 9 AM to 7 PM, Wednesday through Thursday 9 AM to 5 PM, Friday 8 AM to 5 PM, and Saturday 9 AM to 3 PM.

For more on how ketamine therapy works, see our complete guide to ketamine therapy.

What People Like

Dr. Masci administered Western New York’s first Spravato treatment — nearly a decade of clinical experience. SPRAVATO REMS-certified facility. Saturday hours 9 AM to 3 PM — rare for interventional psychiatry. Tuesday hours until 7 PM. Spravato + TMS under one roof for modality flexibility. Integrated psychiatric medical home — medication management, counseling, interventional treatments. Historic Allentown District location walkable from downtown Buffalo.

What People Don’t Like

No IV ketamine option — Spravato only for ketamine-class treatment. No formal KAP model. Pricing not published (insurance-dependent). Single-physician practice means limited appointment capacity. Downtown Buffalo parking may be challenging.

Getting Started at Landmark Health Systems

Call (716) 462-0284 (press option 1 for Spravato inquiries). Visit jarodmascimd.com/spravato-esketaminetherapy. Located at 387 Franklin Street, Buffalo, NY 14202. Verify insurance coverage during intake — Landmark accepts most major plans.

Learn more about the evidence behind ketamine for depression at the National Institute of Mental Health.