Product Description
Known For: Knoxville’s most insurance-accessible Spravato provider — in-network with Aetna, Blue Cross Blue Shield, Cigna, Medicare, TRICARE, and United Healthcare, making treatment-resistant depression treatment financially realistic for working patients.
| Review Scores | Regional behavioral health network with Spravato REMS certification and in-network insurance |
| Location | Knoxville, TN |
| Address | 10133 Sherrill Boulevard, Suite 220, Knoxville, TN 37932 |
| Phone | (615) 320-1155 |
| Website | athenacare.health |
| Treatments | Spravato (Esketamine) Nasal Spray, Psychiatric Services, Mental Health Testing, Therapy |
| Conditions Treated | Treatment-Resistant Depression, Major Depressive Disorder, Suicidal Ideation |
| Cost | Medication $590–$885 per treatment; session $250 (~2 hours); total per session $840–$1,135 |
| Insurance | In-network with Aetna, Blue Cross Blue Shield, Cigna, Medicare, United Healthcare, TRICARE |
| Clinical Lead | Multi-clinician psychiatric team |
HealingMaps Take: Athena Care solves what is arguably the biggest problem in the ketamine-class treatment market: cost. By being in-network with Aetna, Blue Cross Blue Shield, Cigna, Medicare, TRICARE, and United Healthcare — essentially every major insurer a Knoxville patient is likely to have — Athena Care makes Spravato realistically affordable for patients who would otherwise face $800–$1,135 per session out of pocket. That insurance breadth is unusual for interventional psychiatry and reflects a practice genuinely engineered for access rather than boutique private-pay economics. The Cedar Bluff location is convenient for west Knoxville patients, and being part of a larger multi-location Tennessee behavioral health network means patients have continuity if they relocate or travel within the state. Spravato requires administration at a REMS-certified facility under medical supervision due to FDA safety requirements, and Athena Care meets those standards. Limitations: they don’t offer IV ketamine, so patients who specifically want the infusion route need to look elsewhere. For working-class and middle-income Knoxville patients with treatment-resistant depression who need insurance-covered access to ketamine-class treatment, Athena Care is the default answer.
Patient Review
“The cost difference between Spravato here vs. IV ketamine at other Knoxville clinics was the deciding factor for my family. Athena Care took my Blue Cross plan and I ended up paying a small copay per session instead of $600+ out of pocket. The Spravato worked for my depression and my wallet survived.”
About Athena Care
Athena Care is a regional Tennessee behavioral health network with a Knoxville location at 10133 Sherrill Boulevard, Suite 220, Knoxville, TN 37932. The clinic is certified under the Spravato REMS (Risk Evaluation and Mitigation Strategy) program and offers Spravato (esketamine) nasal spray for treatment-resistant depression. Athena Care is in-network with Aetna, Blue Cross Blue Shield, Cigna, Medicare, United Healthcare, and TRICARE. Treatment sessions include the $590–$885 medication cost plus a $250 two-hour clinical session. Additional services include psychiatric evaluation, mental health testing, and therapy.
For more on how ketamine therapy works, see our complete guide to ketamine therapy.
What People Like
In-network with nearly every major insurance plan — Aetna, BCBS, Cigna, Medicare, United, TRICARE. Most financially accessible Spravato provider in Knoxville. Part of a larger multi-location Tennessee network for continuity of care. Spravato REMS-certified facility. Integrated psychiatric services and therapy available alongside Spravato.
What People Don’t Like
No IV ketamine option — Spravato only. Tennessee-wide phone number (615 area code) may feel less local. Lead clinician names not prominently featured for Knoxville specifically. Spravato requires two-hour monitored sessions which is a larger time commitment than some alternatives. No formal KAP model.
Getting Started at Athena Care
Call (615) 320-1155 or 1-877-641-1155, or visit athenacare.health/services/spravato-knoxville. Located at 10133 Sherrill Boulevard, Suite 220, Knoxville, TN 37932. Verify your insurance coverage during intake — most major Tennessee plans are in-network for this location.
Learn more about the evidence behind ketamine for depression at the National Institute of Mental Health.


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