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Patients who did MDMA-assisted therapy saw improvements in their family, social and work life. By one measure, MDMA-assisted therapy was about twice as effective as therapy alone. “It confirms MDMA works,” a psychopharmacologist said. FDA approval could come in a year or so.
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Despite its widespread use and growing popularity, some people worry: if I use MDMA, will it show up on a drug test? Let's dig in.
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Last reviewed and updated: June 22, 2026. Key Takeaways Quality marker Alkaloid standardization (mesembrine % specified) + third-party CoA; “Sceletium extract” without alkaloid content = no reliability guide Best-studied extract Zembrin (25:1, specific alkaloid ratio) — used in published human RCTs for cognitive flexibility and amygdala reactivity Critical warning DO NOT combine with SSRIs, SNRIs, […]
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Last reviewed and updated: June 21, 2026. Key Takeaways Mechanism Serotonin transporter (SERT) inhibition + PDE4 inhibition — distinct from MDMA; closer to mild SSRI-plus-nootropic Effects Mood elevation, calm well-being, reduced anxiety, mild empathogenic warmth; no visual hallucinations; 1–3 hour duration Key research Zembrin RCT: improved cognitive flexibility + executive function; amygdala reactivity reduction (anxiolytic […]
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How Healing REIT, a Real Estate Investment Trust (REIT) is revolutionizing psychedelic therapy and mental health
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Molly (MDMA) Powder is an illicit drug on the street, but some are finding it useful for psychedelic therapy.
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Champagne and MDMA? Multiple Moët bottles recalled after traces of psychedelic found.
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A big change to psychedelic therapy treatments could be coming thanks to the Biden administration.
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Everything you need to know about MDMA (Ecstasy)
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Can the use of psychedelics in therapy settings change mental health as we know it?
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