Product Description
✓ Edited by Angelica Bottaro for HealingMaps Editorial Staff
Known For: Fargo (45th St S) ketamine clinic led by board-certified nurse anesthetist Jacqueline Materi, CRNA — IV ketamine plus REMS-certified Spravato for mood disorders and chronic pain. One of North Dakota’s longest-running ketamine providers (Bismarck since 2017, Fargo since 2019).
| Location | Fargo, North Dakota |
| Address | 3441 45th St S, Suite B, Fargo, ND 58104 |
| Phone | Contact clinic for scheduling |
| Website | ketaminecareclinic.com |
| Treatments | IV Ketamine Infusion + Spravato (Esketamine, REMS-certified) |
| Conditions | Depression, anxiety, OCD, PTSD; plus chronic pain conditions (fibromyalgia, migraines, CRPS) |
| Cost | N/A (contact for pricing) |
| Insurance | Spravato typically insurance-billed; IV ketamine self-pay (FSA/HSA eligible) |
| KAP Available | No |
| Clinical Lead | Jacqueline Materi, APRN, CRNA (board-certified nurse anesthetist) |
HealingMaps Take: Ketamine Care Clinic brings genuine depth to the Fargo market — Jacqueline Materi, CRNA, was an early North Dakota ketamine pioneer (Bismarck 2017), and the clinic pairs IV ketamine with insurance-billable Spravato, which matters in a rural market where cost is a real barrier. The dual mental-health-plus-chronic-pain focus and CRNA anesthesia background make it a strong, established option for eastern North Dakota and western Minnesota.
Market Position: Ketamine Care Clinic occupies the CRNA-led, established-provider slot in the Fargo–Moorhead market — IV ketamine + Spravato from one of the state’s first ketamine practices. Distinct from the other Fargo options (Fargo Ketamine Clinic, Renewed Wellness). The long track record and Spravato access are the differentiators.
Is Ketamine Care Clinic Right for You?
✓ Choose Ketamine Care Clinic if:
- You want both IV ketamine and insurance-billable Spravato from one Fargo practice
- You value an established, early-adopter ketamine provider (operating in ND since 2017)
- You’re in Fargo, West Fargo, Moorhead, or eastern North Dakota / western Minnesota
- You’re treating depression, anxiety, OCD, or PTSD — or chronic pain (fibromyalgia, migraines, CRPS)
- You prefer CRNA-supervised infusions
✗ Look elsewhere if:
- You want a psychiatrist-led practice with full medication management
- You’re seeking structured ketamine-assisted psychotherapy (KAP) with an embedded therapist
- You need a clinic in central/western North Dakota (this clinic’s sister location is in Bismarck)
Ketamine Care Clinic Ketamine Cost Calculator
How Much Will Ketamine Therapy Cost?
Ketamine Protocols Compared — What’s Offered at Ketamine Care Clinic
Industry pricing reference. Ketamine Care Clinic has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.
| Protocol | Typical Industry Cost | Offered Here |
|---|---|---|
| IV Ketamine | $350–$650/session | ✓ Yes |
| Spravato (esketamine) | $0–$250 copay (insured) | ✓ Yes |
| IM Ketamine | $250–$400/injection | — |
| KAP (with therapist) | $400–$1,200/session | — |
| At-home troches | $150–$300/month | — |
What to Expect at Your First Ketamine Care Clinic Appointment
- Initial intake call — Insurance verification, Spravato prior authorization workflow if applicable, and clinical eligibility check. Visit ketaminecareclinic.com to book an intake.
- Medical evaluation — psychiatric assessment, vitals check, and review of current medications and prior treatment history with the Ketamine Care Clinic clinical team.
- First treatment session — supervised ketamine session in a monitored treatment room at 3441 45th St S, Suite B, Fargo, ND 58104.
- Recovery and follow-up — observation period after dosing, mood check-in with the clinical team, and scheduling your next session.
What to Ask on Your Ketamine Care Clinic Consult Call
- How long has the Ketamine Care Clinic clinical team been delivering ketamine therapy, and what specialty training do your providers hold?
- Walk me through your Spravato prior authorization process vs. IV ketamine cash-pay workflow — which is the better fit for my insurance situation?
- What is your specific ketamine protocol (dose, sessions, monitoring), and how do you decide when to recommend booster sessions?
- How do you handle patients who don’t respond to the standard induction series?
Fargo Ketamine Market Snapshot
Sources: CDC PLACES 2023 (Cass County (Fargo–Moorhead metro / eastern North Dakota), crude prevalence) · U.S. Census ACS 5 Year · HealingMaps proprietary patient inquiry data.
- Adult depression in Cass County (Fargo–Moorhead metro / eastern North Dakota): 16.7%
- Frequent mental distress (14+ days per month): 13.4%
- Adults lacking health insurance: 8.7%
- Cass County (Fargo–Moorhead metro / eastern North Dakota) population: 249,843 · median household income $66,222
- Recent Fargo-area inquiries to HealingMaps: A growing stream of Fargo-area residents have recently contacted us seeking ketamine care
Behind this data: HealingMaps has analyzed 23,496 patient inquiries (Oct 2022 – Mar 2026), mapped 1,800 verified clinics across 3,142 counties, scraped 132 clinic pricing pages, and collected 658 practitioner survey responses. This snapshot reflects our multi-source methodology.
From the 2026 Ketamine Industry Report
44.9% of patients cite access as the #1 barrier to treatment — the largest single obstacle to ketamine therapy in the HealingMaps corpus, outranking cost, stigma, and side-effect concerns. Source: HealingMaps 2026 Ketamine Clinic Intelligence Report — drawn from 23,496 patient inquiries and 132 clinic website analyses.
Patient Review
“Jacqueline has been doing this in North Dakota longer than anyone — that experience showed. Being able to use Spravato through my insurance made it affordable in a way IV alone wouldn’t have been.”
About Ketamine Care Clinic
Ketamine Care Clinic operates from 3441 45th St S, Suite B in Fargo, ND (58104), serving the Fargo–Moorhead metro and eastern North Dakota / western Minnesota. It is led by Jacqueline Materi, APRN, CRNA, a board-certified nurse anesthetist who opened North Dakota’s first ketamine clinic in Bismarck in 2017 and added the Fargo location in 2019.
The clinic offers IV ketamine infusions and Spravato (esketamine) under FDA REMS certification. The Spravato pathway is insurance-billable, an important access factor in a rural market where out-of-pocket IV ketamine can be a barrier.
Conditions treated include depression, anxiety, OCD, and PTSD, as well as chronic pain conditions such as fibromyalgia, migraines, and complex regional pain syndrome (CRPS). The clinic’s long operating history and CRNA anesthesia background make it one of the most established interventional options in the region.
Ketamine Care Clinic also operates a Bismarck location. To schedule, visit ketaminecareclinic.com.
Patient Questions about Ketamine Care Clinic
This 5-question summary is matched to the protocols and conditions Ketamine Care Clinic treats. Editorial responses are HealingMaps-authored.
What ketamine protocols does Ketamine Care Clinic offer?
Ketamine Care Clinic offers IV Ketamine Infusion + Spravato (Esketamine, REMS-certified). Confirm specific dosing schedules during your consult.
Does Ketamine Care Clinic offer Spravato (esketamine)?
Yes — Ketamine Care Clinic offers Spravato, which means they’re FDA REMS-certified and maintain the required two-hour in-office monitoring window after each dose.
Does Ketamine Care Clinic offer ketamine-assisted psychotherapy (KAP)?
Ketamine Care Clinic operates a medical-model program. Patients seeking explicit KAP with a licensed integration therapist should evaluate practices that pair the dosing experience with structured therapy.
Is Ketamine Care Clinic suited for treatment-resistant depression?
Ketamine Care Clinic treats treatment-resistant depression. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates.
Can Ketamine Care Clinic help with anxiety disorders?
Yes — Ketamine Care Clinic treats anxiety disorders. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines.
View all REMS-certified Spravato clinics in North Dakota and across the United States.
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