Product Description

Known For: Knoxville’s locally-owned ketamine clinic offering both IV ketamine and Spravato under one roof — distinguished by published pricing transparency and a non-corporate, community-oriented practice model.

HealingMaps Take: 865 Wellness + Ketamine occupies an important position in the Knoxville market as a locally-owned alternative to the larger multi-state chains (Revitalist) that dominate Tennessee ketamine treatment. Local ownership matters clinically because it often means consistency in clinicians, more personalized care, and pricing that reflects local market conditions rather than national corporate models. Their offering of both IV ketamine and Spravato means patients don’t need to choose a clinic based on which treatment they want — the clinic meets them wherever they are in their treatment journey. The published pricing transparency (rare in the Knoxville market) signals a practice confident in its clinical value and willing to compete on trust rather than opacity. The South Concord Street location on the west side of Knoxville near Bearden is convenient for patients from Cedar Bluff, Farragut, and the west Knoxville corridor. For Knoxville patients who want a locally-accountable ketamine clinic rather than a national chain, 865 Wellness is the clear choice.

Patient Review

“865 Wellness has a small-town feel that the bigger chains just can’t replicate. Jennifer and the team remember you by name, they take the time to actually check in between infusions, and the Spravato option meant I could use my insurance when the IV ketamine became too expensive.”

About 865 Wellness + Ketamine

865 Wellness + Ketamine is a locally-owned infusion therapy clinic at 601 S Concord Street, Suite 100, Knoxville, TN 37919. The clinic offers IV ketamine infusion therapy, Spravato (esketamine) nasal spray for treatment-resistant depression, and IV vitamin therapy. Treatment conditions include depression, anxiety, PTSD, OCD, chronic pain, and bipolar depression. The west Knoxville location serves the Bearden, Cedar Bluff, Farragut, and west Knoxville corridor.

For more on how ketamine therapy works, see our complete guide to ketamine therapy.

What People Like

Locally owned and operated — not a chain. Offers both IV ketamine and Spravato under one roof. Published pricing page available (rare for Knoxville ketamine). West Knoxville location convenient for Bearden/Cedar Bluff/Farragut patients. Small-team model means clinician continuity between sessions. Patient reviews consistently praise staff attentiveness.

What People Don’t Like

IV ketamine is self-pay only. Lead clinician credentials not prominently featured on website. No formal KAP program. No weekend availability confirmed. Small scale may mean longer wait times for appointments compared to larger clinics.

Getting Started at 865 Wellness + Ketamine

Call (865) 805-3118 or visit 865wellnessketamine.com. Located at 601 S Concord Street, Suite 100, Knoxville, TN 37919. Ask about Spravato insurance coverage during intake — most major insurance plans cover Spravato for treatment-resistant depression.

Learn more about the evidence behind ketamine for depression at the National Institute of Mental Health.