Product Description

Known For: Cincinnati’s most holistic ketamine-assisted psychotherapy practice, integrating KAP with art therapy, acupuncture, Traditional Chinese Medicine, bodywork, and somatic practices — all under physician supervision with a 5.0 Google rating.

HealingMaps Take: One Heart Mental Health Collaborative is doing something genuinely different in the Cincinnati ketamine space. While most clinics offer infusions and maybe a therapy referral, One Heart builds an entire healing ecosystem around the ketamine experience — art therapy, bodywork, somatic practices, acupuncture, Traditional Chinese Medicine, nutrition counseling, and group integration circles. This is not a medical model with add-ons; it is a holistic healing model that uses ketamine as one catalyst among many. Dr. James Weeks brings a rare combination of credentials: board-certified in internal medicine (he understands the medical side) with year-long psychedelic facilitator training through SoundMind in Philadelphia (he understands the therapeutic side). Both a physician and a licensed therapist are present throughout every KAP session — a level of dual oversight that few clinics match. The pricing is transparent and competitive: $750 for the first round (which includes medical intake, preparation, the medicine session, and integration) and $550 for subsequent rounds. The 5.0 Google rating with consistent praise suggests this model is working. For patients who see their depression or trauma as a whole-person issue rather than a brain chemistry problem, One Heart is the most integrative option in the Cincinnati region.

Patient Review

“One Heart is unlike any mental health practice I have experienced. The KAP sessions with Dr. Weeks were transformative, but what made the real difference was the integration — the art therapy, the bodywork, the group circles. It felt like healing on every level, not just medicating symptoms.”

About One Heart Mental Health Collaborative

One Heart Mental Health Collaborative is a holistic ketamine-assisted psychotherapy practice located at 455 Delta Ave, Suite 303B, Cincinnati, OH 45226. Founded by Dr. James Michael Weeks — board-certified in internal medicine with year-long psychedelic facilitator training through SoundMind — the practice offers KAP with a physician and therapist present throughout every session, plus Spravato, art therapy, bodywork, somatic and mindfulness practices, acupuncture, Traditional Chinese Medicine, nutrition counseling, and group integration therapy. One Heart has a 5.0 Google rating.

For more on how ketamine therapy works, see our complete guide to ketamine therapy.

What People Like

Most holistically integrative ketamine practice in Cincinnati. Physician AND therapist present throughout every KAP session. Art therapy, acupuncture, bodywork, TCM complement the ketamine work. Transparent pricing: $750 first round, $550 subsequent. 5.0 Google rating. Dr. Weeks has both MD and psychedelic facilitator credentials. Group integration circles build patient community. Free 15-minute consultations.

What People Don’t Like

No IV ketamine — KAP model uses IM/oral dosing. Self-pay only — no direct insurance billing. Relatively new practice (established 2024). Solo physician model may limit scheduling. East Side location may be inconvenient for west-side Cincinnati residents. The holistic approach may not appeal to patients wanting a straightforward medical model.

Getting Started at One Heart Mental Health Collaborative

Call (513) 212-5482 or visit oneheartmentalhealthcollab.com to book a free 15-minute consultation. Located at 455 Delta Ave, Suite 303B, Cincinnati, OH 45226. First KAP round is $750 (includes intake, preparation, medicine session, and integration).

Learn more about the evidence behind ketamine for depression at the National Institute of Mental Health.