Product Description
Known For: The first civilian TMS center in Hawaii, the first on Oahu to use pharmacogenomics, and a REMS-certified Spravato (esketamine) center — Hawaii’s most established interventional psychiatry practice.
| Review Scores | Pioneer in interventional psychiatry in Hawaii |
| Location | Honolulu, HI |
| Address | 1164 Bishop St, Suite 1611, Honolulu, HI 96813 |
| Phone | (808) 261-7792 |
| Website | apt-hi.com |
| Treatments | Spravato (Esketamine Nasal Spray, REMS-Certified), TMS/Theta Burst Stimulation, Psychiatry |
| Conditions Treated | Treatment-Resistant Depression, General Psychiatric Conditions |
| Cost | Contact clinic for pricing |
| Insurance | Accepts many insurance types (Spravato typically covered by insurance) |
| Clinical Lead | Psychiatric team (first civilian TMS center in Hawaii; first on Oahu to use pharmacogenomics) |
HealingMaps Take: Advanced Psychiatric Therapeutics (APT) is Hawaii’s interventional psychiatry pioneer. As the first civilian TMS center in the state and the first practice on Oahu to implement pharmacogenomic testing, APT has consistently been years ahead of the local market. Their REMS-certified Spravato program adds FDA-approved esketamine nasal spray to the arsenal, and because Spravato is typically covered by insurance, this is one of the few Hawaii practices where patients can access ketamine-class treatment without paying entirely out of pocket. The downtown Honolulu location at Bishop Street puts the clinic in the heart of the business district — convenient for working professionals who need lunchtime or after-work appointments. For patients who want the insurance coverage advantage of Spravato combined with the option to add TMS, APT offers the most established and insurance-friendly interventional psychiatry program in the state.
Patient Review
“APT was the first practice in Hawaii that offered me something beyond traditional medication. The Spravato program was covered by my insurance, which made a treatment I thought was out of reach suddenly affordable.”
About Advanced Psychiatric Therapeutics
Advanced Psychiatric Therapeutics (APT) is a pioneering interventional psychiatry practice in downtown Honolulu at 1164 Bishop St, Suite 1611. The practice holds multiple firsts in Hawaii: the first civilian TMS center in the state, the first practice on Oahu to use pharmacogenomic testing, and a REMS-certified Spravato (esketamine) treatment center. APT offers Spravato nasal spray, TMS with theta burst stimulation, and comprehensive psychiatric services for treatment-resistant depression and general psychiatric conditions. Spravato is typically covered by major insurance plans.
For more on how ketamine therapy works, see our complete guide to ketamine therapy.
What People Like
REMS-certified Spravato center — one of the few insurance-covered ketamine-class treatment options in Hawaii. The first civilian TMS center in the state, with deep institutional experience. Pharmacogenomic testing can help identify why previous medications failed. Downtown Honolulu Bishop Street location is accessible for working professionals. Accepts many insurance types, reducing out-of-pocket costs significantly compared to IV ketamine clinics.
What People Don’t Like
Does not offer IV ketamine infusions — only Spravato (esketamine nasal spray). KAP is not available. Spravato requires a 2-hour in-office monitoring period per REMS protocol. The practice focuses on depression — patients with chronic pain or other conditions may need a different provider. Specific provider names and credentials are not prominently published on the website.
Getting Started at Advanced Psychiatric Therapeutics
Call (808) 261-7792 or visit apt-hi.com to schedule a psychiatric evaluation. Ask about Spravato insurance coverage and the TMS program. The office is at 1164 Bishop St, Suite 1611, Honolulu, HI 96813.
Learn more about the evidence behind ketamine for depression at the National Institute of Mental Health.


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