Product Description
Known For: Harvard-affiliated academic medical center ketamine program — the gold standard in clinical research and evidence-based ketamine treatment.
| Review Scores | Harvard-affiliated academic medical center; leading ketamine research institution |
| Location | Boston, MA |
| Address | Wang Building, Massachusetts General Hospital, Boston, MA 02114 |
| Phone | (617) 724-5510 |
| Website | massgeneral.org |
| Treatments | IV Ketamine, Esketamine (Intranasal) |
| Conditions Treated | Treatment-Resistant Depression, Major Depressive Disorder |
| Cost | Contact clinic for pricing |
| Insurance | Contact clinic; esketamine may be covered by insurance |
| Clinical Lead | Dr. Cristina Cusin, MD |
HealingMaps Take: Mass General Hospital’s IV Ketamine Clinic represents the apex of evidence-based ketamine treatment in Boston — and arguably in the entire country. Led by Dr. Cristina Cusin, MD, the program operates within the research and clinical infrastructure of Massachusetts General Hospital, Harvard Medical School’s largest teaching hospital. This is not a standalone infusion clinic; it is an academic medical center program backed by decades of institutional expertise in psychiatry, anesthesiology, and clinical research. For patients who prioritize clinical rigor, safety infrastructure, and access to the latest research protocols, MGH is the definitive choice. The clinic offers both IV ketamine and intranasal esketamine, and the hospital setting provides a level of emergency response capability that no outpatient clinic can match.
Patient Review
“Being treated at Mass General gave me a level of confidence that no standalone clinic could. Dr. Cusin and the team were thorough, evidence-driven, and genuinely invested in my progress.”
About Mass General Hospital IV Ketamine Clinic
The Mass General Hospital IV Ketamine Clinic is a specialized program within the Department of Psychiatry at Massachusetts General Hospital, Harvard Medical School’s largest teaching hospital. The clinic is led by Dr. Cristina Cusin, MD, and offers both IV ketamine infusions and intranasal esketamine (Spravato) for treatment-resistant depression and major depressive disorder. Located in the Wang Building, the program operates within the full clinical infrastructure of a world-class academic medical center. Referrals and inquiries can be directed to (617) 724-5510 or mghketamineclinic@mgh.harvard.edu.
For more on how ketamine therapy works, see our complete guide to ketamine therapy.
What People Like
The Harvard/MGH affiliation provides unmatched clinical credibility and research access. Dr. Cristina Cusin is a recognized leader in ketamine research. The hospital setting offers the highest level of safety infrastructure and emergency response. Both IV ketamine and intranasal esketamine are available. Patients may have access to clinical trials and emerging protocols.
What People Don’t Like
Academic medical center scheduling can be slower and more bureaucratic than private clinics. The clinic focuses narrowly on depression — patients with anxiety, PTSD, or chronic pain may need to look elsewhere. KAP is not offered. The hospital environment may feel clinical rather than calming. Parking and navigation at MGH can be challenging.
Getting Started at Mass General Hospital IV Ketamine Clinic
Call (617) 724-5510 or email mghketamineclinic@mgh.harvard.edu to schedule a consultation. The clinic is in the Wang Building at Massachusetts General Hospital, Boston. Mailing address: One Bowdoin Square, 6th Floor, Boston, MA 02114.
Learn more about the evidence behind ketamine for depression at the National Institute of Mental Health.


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